Additive manufacturing of “polypill” capsules of complex geometry with individualised release

capsules

A Presentation by Beatriz Pereira, Scientist, University of Central Lancashire

Polypharmacy is often needed for the management of chronic conditions and is usually associated with poor patient adherence. Therefore, easily personalised systems are necessary to accommodate complex therapeutic regimens.

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Additive Manufacturing: Unlocking Pharma’s Unmet Challenges

Jae Yoo

A presentation by Jae Yoo, CTO of Aprecia Pharmaceuticals. He is serving as Chief Technology Officer for Aprecia Pharmaceuticals, LLC since August 2018. His 3DP journey started at MIT in the early 1990’s where he developed and used an inkjet printing based 3DP process to fabricate advanced ceramic materials with compositional gradient.

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Additive Manufacturing of Tablets

Christoph Hüls

presentation by Christoph Hüls, Founder Additive Manufacturing of Tablets, Merck Innovation Center, Merck KGaA

Additive Manufacturing of Tablets has the potential to simplify the manufacturing of pills (tablets). Instead of a multistep complicated process, a three step process (mixing a powder formulation, printing the tablets in the printer and coating of the tablets) will lead to cost and time savings for customers.

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Challenges and opportunities of 3D-printed drugs for the hospital pharmacy

Josep Guiu

presentation by Josep M Guiu, Head of pharmaceutical planning and pharmacotherapy coordination at the Catalan Health and Social Care Consortium in Barcelona, Spain.

There is a huge potential of 3D printing to revolutionise clinical pharmacy practice with the development of a new generation of personalized compounded drugs. The implementation of a 3D printer into a hospital pharmacy could make possible to individualize shapes, sizes and dosages of several oral drugs to patients.

However, its implementation needs the collaboration of hospital pharmacists with pharmaceutical scientists and the pharmaceutical industry, as well as to define a new regulatory framework for these new drugs.

program: https://www.3dpharmaprintingconference.com/speakers/

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Use of 3D printing for therapy production in a clinical setting

Alvaro Goyanes

presentation by Alvaro Goyanes, Co-founder and Director of Development, FabRX

3D printing (3DP) is an increasingly growing manufacturing technology that provides the ability to fabricate structures of precise geometries from a 3D model by deposition of many thin layers. 3DP is nowadays used as a production tool or for rapid prototyping in many areas.

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Pharma and Food get personalized with 3D Printing! (VIDEO)

tno

states Kjeld van Bommel, Senior Researcher at TNO during his interview for JakajimaTV hosted by Pieter Hermans. TNO has been active in the area of 3D Pharma and 3D Food Printing since 2011. Based on its combined knowledge and expertise on 3D printing as well as Pharma and Food, TNO has been able to help organisations to develop exciting new products and services.

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3D powder bed printing with lactose: a showcase

korinde van den heuvel

by Korinde van den Heuvel, Senior Product Developer, DFE Pharma

3D printing offers huge potential benefits in pharmaceutical manufacturing, like creating fast and reliable wide dosed dosage forms for clinical use and ability to tailor dose in dosage forms for specific user groups. In order to embrace this new world of opportunities, there is a need for thorough understanding of the powder physics of the materials, processes and techniques involved. Powder bed printing, which has been used to develop Spritam, is arguably the best method for pharmaceutical manufacturing.

Powder physics like, flowability, wettability and consolidation of the blend are critical material attributes for powder bed printing and will impact the tablet functionality like hardness, disintegration and friability. Limited information is available on excipient selection in relationship to functionality in the dosage form in literature.

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