A clear unmet medical need exists for pediatric-centered drug formulations. Currently, it is often still necessary to either manipulate a marketed drug before it can be administered to a child, or to prepare an extemporaneous preparation by the pharmacist. As a highly flexible production technique, 3D printing can provide in this unmet need.
In this presentation, the product development of two active pharmaceutical ingredients, namely furosemide and sildenafil, will be presented.
Continue reading “3D printing tablets for individual pediatric patients: development of furosemide and sildenafil tablets”
Need for personalized dosage forms. Due to the lack of age-appropriate formulations for children, healthcare professionals and caregivers frequently manipulate dosage forms to facilitate oral administration and obtain the required dose. In this presentation, drug manipulation and age-appropriateness of oral medications for pediatric oncology and neurology patients are summarised with the aim of identifying the therapeutic needs for personalized dosage forms.
Continue reading “Manipulations and age-appropriateness of oral medications in pediatric oncology and neurology patients in Sweden”
Interview with Beatriz Pereira, University of Central Lancashire, for JakajimaTV hosted by Pieter Hermans. Current healthcare follows an ‘one size fits all’ approach, and it is associated with high variations in treatment outcomes, due to the high interindividual variability.
Continue reading “3D printing of modular ‘polypills’ for personalised therapy”